Betapol® | Bunge Loders Croklaan
Closer to nature every day
The ideal choice for infant formula

Breastfeeding is an important bonding experience and provides babies with the best start in life. When breastfeeding is not an option, choosing the best infant formula is key for healthy growth and development.

The inventor of OPO

Fats are an essential nutrient for the baby. While mother’s milk fat contains only 3-4% fat it makes up 50% of a baby’s energy intake. Betapol is the ideal choice of fat for infant formula because it mimics the fat composition and unique OPO fat structure that is naturally present in mother’s milk, allowing babies to absorb more palmitic acid and calcium which contributes to significant nutritional benefits. That's why it's widely trusted as the standard for OPO fats. 

Over 30 years ago we invented OPO, bringing infant formula closer to nature. In 2019 we revolutionized the market again with Betapol Plus, the next generation OPO. It is designed to match mothers’ milk fat more closely, by combining the benefits of OPO with the highest OPO/SN-2 palmitate levels available on the market.

OPO Benefits
Improved energy intake
Reduced constipation
Increased bone mineral density
Healthier gut bacteria
Less crying
Better sleep
Improved fine motor skills
OPO Benefits
Latest OPO study shows new benefit

Recent independent clinical research* published in February 2021 indicates a positive effect  on the Bifidobacteria level in the infant's gut and fine motor skills. This cluster randomized clinical trial enrolled 199 infants: 66 infants were breast-fed and 133 infants received formula: 
- 66 infants received formula containing high SN-2 palmitate with 46.3% of the palmitic acid in the SN-2 position. The content of the SN-2 PA level in the high SN-2 palmitate formula was increased by adding Betapol produced by Bunge Loders Croklaan
- 67 infants in the control group received formula containing low SN-2 palmitate with 10.3% of the palmitic acid in the SN-2 position from a standard vegetable oil mixture.

The conclusion of the trial states that "Elevating the SN-2 palmitate level in the formula improved infants’ development of fine motor skills, and the beneficial effects of high SN-2 palmitate on infant neurodevelopment was associated with the increased gut Bifidobacteria level."

*The trial is published on MDPI's website: Nutrients | Free Full-Text | Neurodevelopmental Outcomes and Gut Bifidobacteria in Term Infants Fed an Infant Formula Containing High sn-2 Palmitate: A Cluster Randomized Clinical Trial | HTML (

Nutra-Ingredients published about the research and its findings here: Infant neurodevelopment: Higher intake of sn-2 palmitate could improve fine motor skills and increase gut Bifidobacteria – China study (

Read our Scientific Summary for a total overview of all clinical studies backing the benefits of OPO.

OPO explained

Many standard infant milk formulas have a fat structure (POP) that resembles breast milk fat, but the fatty acids are positioned differently. The fatty acid composition of Betapol mimics the unique OPO structure naturally present in in breast milk. As a result, it optimizes absorption of palmitic acid and calcium which are crucial to energy intake and bone formation.

Innovation today and tomorrow

Together with established infant nutrition authorities in Europe, we have committed to a major long-term research program to identify and substantiate new Betapol® benefits. These studies have already indicated that Betapol® has a positive impact on brain function and physical development. These SN-2 palmitate fat innovations will enable us to extend the Betapol® portfolio and further develop new OPO products and product combinations adding value to your brand.

Contact our team
Enabling your brand
Over 30 years ago, we invented the process behind Betapol®. With our extensive technical and applications expertise, we can help you identify the right Betapol® blend for your products and maximize your brand impact.